*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 28.00 | Week 11, 2018 * | LAR | KCKC | 2 Tackles, 1 Assist, 1.0 Sack, 1 Int, 3 TD, 1 Fum Rcvy, 1 PD |
| 2. | 17.00 | Week 13, 2023 | Ind | @Ten@Ten | 5 Tackles, 1 Assist, 2.0 Sacks, 1 FF |
| 3. | 15.00 | Week 12, 2023 | Ind | TBTB | 3 Tackles, 1 Assist, 2.0 Sacks, 1 FF |
| 3. | 15.00 | Week 04, 2022 | SF | LARLAR | 3 Tackles, 1 Assist, 2.0 Sacks, 1 FF |
| 3. | 15.00 | Week 12, 2019 | LAR | BalBal | 3 Tackles, 6 Assists, 1.5 Sacks |
| 6. | 13.00 | Week 14, 2019 | LAR | SeaSea | 4 Tackles, 1 Assist, 2.0 Sacks |
| 7. | 12.00 | Week 17, 2020 | LAR | ARIARI | 4 Tackles, 2.0 Sacks |
| 7. | 12.00 | Week 15, 2020 | LAR | NYJNYJ | 3 Tackles, 2 Assists, 1.0 Sack, 1 FF |
| 9. | 11.00 | Week 03, 2023 | Ind | @Bal@Bal | 4 Tackles, 1.0 Sack, 1 FF |
| 10. | 10.00 | Week 16, 2021 | SF | @TEN@TEN | 3 Tackles, 1 Assist, 1.5 Sacks |
| 10. | 10.00 | Week 07, 2018 | LAR | @SF@SF | 3 Tackles, 1.0 Sack, 1 FF |
| 12. | 9.00 | Week 15, 2023 | Ind | PitPit | 2 Tackles, 1 Assist, 1.5 Sacks |
| 13. | 8.00 | Week 06, 2022 | SF | @Atl@Atl | 5 Tackles, 3 Assists |
| 13. | 8.00 | Week 14, 2021 | SF | @CIN@CIN | 3 Assists, 0.5 Sack, 1 FF |
| 13. | 8.00 | Week 10, 2017 | LAR | HouHou | 1 Tackle, 1.0 Sack, 1 FF |
| 16. | 7.00 | Week 06, 2023 | Ind | @Jac@Jac | 3 Tackles, 1.0 Sack |
| 16. | 7.00 | Week 05, 2023 | Ind | TenTen | 2 Tackles, 1 Assist, 1.0 Sack |
| 16. | 7.00 | Week 15, 2021 | SF | ATLATL | 3 Tackles, 1.0 Sack |
| 16. | 7.00 | Week 11, 2020 | LAR | @TB@TB | 3 Tackles, 1.0 Sack |
| 16. | 7.00 | Week 01, 2019 | LAR | @Car@Car | 1 Tackle, 1 FF, 1 Fum Rcvy |
| 21. | 6.00 | Week 02, 2023 | Ind | @Hou@Hou | 2 Tackles, 1.0 Sack |
| 21. | 6.00 | Week 15, 2022 | SF | @Sea@Sea | 1 Tackle, 1.0 Sack, 1 PD |
| 21. | 6.00 | Week 01, 2022 | SF | @CHI@CHI | 2 Tackles, 1.0 Sack |
| 21. | 6.00 | Week 08, 2021 | SF | @CHI@CHI | 2 Tackles, 1.0 Sack |
| 21. | 6.00 | Week 04, 2020 | LAR | NYGNYG | 1 Tackle, 3 Assists, 0.5 Sack |
| 21. | 6.00 | Week 06, 2019 | LAR | SFSF | 2 Tackles, 4 Assists |
| 21. | 6.00 | Week 12, 2017 | LAR | NONO | 1 Tackle, 1 Assist, 1.0 Sack |
| 28. | 5.00 | Week 07, 2023 | Ind | CleCle | 3 Tackles, 1 Assist, 1 PD |
| 28. | 5.00 | Week 12, 2022 | SF | NONO | 1 Tackle, 1 Assist, 1 Fum Rcvy |
| 28. | 5.00 | Week 17, 2021 | SF | HOUHOU | 1 Tackle, 2 Assists, 0.5 Sack |
| 28. | 5.00 | Week 16, 2019 | LAR | @SF@SF | 1 Tackle, 1.0 Sack |
| 28. | 5.00 | Week 11, 2019 | LAR | ChiChi | 3 Tackles, 1 Assist, 1 PD |
| 28. | 5.00 | Week 13, 2018 | LAR | @Det@Det | 2 Tackles, 1 Fum Rcvy |
| 28. | 5.00 | Week 09, 2018 | LAR | @NO@NO | 2 Tackles, 1 FF |
| 28. | 5.00 | Week 06, 2018 | LAR | @Den@Den | 1 Tackle, 1 Assist, 1 FF |
| 28. | 5.00 | Week 05, 2018 | LAR | @Sea@Sea | 3 Tackles, 2 Assists |
| 28. | 5.00 | Week 02, 2018 | LAR | AriAri | 1 Tackle, 1.0 Sack |
| 28. | 5.00 | Week 13, 2017 | LAR | @Ari@Ari | 5 Tackles |
| 28. | 5.00 | Week 01, 2017 | LAR | IndInd | 5 Tackles |
| 40. | 4.00 | Week 16, 2023 | Ind | @Atl@Atl | |
| 40. | 4.00 | Week 08, 2023 | Ind | NONO | 3 Tackles, 1 Assist |
| 40. | 4.00 | Week 04, 2023 | Ind | LARLAR | 2 Tackles, 2 Assists |
| 40. | 4.00 | Week 01, 2021 | SF | @DET@DET | 2 Tackles, 2 Assists |
| 40. | 4.00 | Week 12, 2020 | LAR | SFSF | 2 Tackles, 1 Assist, 1 PD |
| 40. | 4.00 | Week 01, 2020 | LAR | DalDal | 2 Tackles, 2 Assists |
| 40. | 4.00 | Week 17, 2019 | LAR | AriAri | 1 Tackle, 1 Fum Rcvy |
| 40. | 4.00 | Week 13, 2019 | LAR | @Ari@Ari | 2 Tackles, 2 Assists |
| 40. | 4.00 | Week 08, 2019 | LAR | CinCin | 2 Tackles, 1 Assist, 1 PD |
| 40. | 4.00 | Week 03, 2019 | LAR | @Cle@Cle | 2 Tackles, 1 Assist, 1 PD |
| 40. | 4.00 | Week 08, 2018 | LAR | GBGB | 2 Tackles, 2 Assists |