*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 17.00 | Week 02, 2022 | Den | HouHou | 4 Tackles, 2 Assists, 2.0 Sacks, 1 FF |
| 2. | 14.00 | Week 16, 2023 | Den | NENE | |
| 3. | 10.00 | Week 13, 2021 | SF | @SEA@SEA | 7 Tackles, 1 FF |
| 4. | 9.00 | Week 05, 2022 | Den | IndInd | 1 Assist, 0.5 Sack |
| 4. | 9.00 | Week 08, 2019 | SF | CarCar | 4 Tackles, 1 Assist, 1.0 Sack |
| 6. | 8.00 | Week 15, 2023 | Den | @Det@Det | 3 Tackles, 1 Assist, 1.0 Sack |
| 6. | 8.00 | Week 09, 2021 | SF | ARIARI | 4 Tackles, 4 Assists |
| 6. | 8.00 | Week 05, 2021 | SF | @ARI@ARI | 4 Tackles, 1.0 Sack |
| 9. | 7.00 | Week 11, 2025 | Den | KC KC | 2 Tack, 1 Ass, 1.00 Sack |
| 9. | 7.00 | Week 17, 2023 | Den | LACLAC | 2 Tackles, 2 Assists, 1 FF |
| 9. | 7.00 | Week 18, 2021 | SF | @LAR@LAR | 1 Tackle, 1 Assist, 1.0 Sack, 1 PD |
| 12. | 6.00 | Week 03, 2025 | Den | @LAC@LAC | 2 Tack, 1.00 Sack |
| 12. | 6.00 | Week 15, 2024 | Den | IndInd | 1 Tack, 2 Ass, 1 Fum Rcvy |
| 12. | 6.00 | Week 12, 2024 | Den | @LV @LV | 1 Tack, 2 Ass, 0.50 Sack, 1 PD |
| 12. | 6.00 | Week 11, 2023 | Den | MinMin | 2 Tackles, 1 Assist, 1 FF |
| 12. | 6.00 | Week 01, 2020 | SF | AriAri | 1 Tackle, 1.0 Sack, 1 PD |
| 17. | 5.00 | Week 17, 2024 | Den | @Cin@Cin | 1 Tack, 2 Ass, 0.50 Sack |
| 17. | 5.00 | Week 13, 2024 | Den | CleCle | 2 Tack, 2 Ass, 1 PD |
| 17. | 5.00 | Week 13, 2023 | Den | @Hou@Hou | 3 Tackles, 2 Assists |
| 17. | 5.00 | Week 10, 2022 | Den | @Ten@Ten | 2 Tackles, 2 Assists, 1 PD |
| 17. | 5.00 | Week 12, 2021 | SF | MINMIN | 2 Tackles, 3 Assists |
| 17. | 5.00 | Week 08, 2021 | SF | @CHI@CHI | 5 Tackles |
| 17. | 5.00 | Week 04, 2021 | SF | SEASEA | 2 Tackles, 1 FF |
| 17. | 5.00 | Week 16, 2020 | SF | @ARI@ARI | 1 Tackle, 1.0 Sack |
| 17. | 5.00 | Week 04, 2020 | SF | PHIPHI | 1 Tackle, 1.0 Sack |
| 17. | 5.00 | Week 14, 2019 | SF | @NO@NO | 1 Tackle, 1 Assist, 1 FF |
| 17. | 5.00 | Week 10, 2019 | SF | SeaSea | 1 Tackle, 1.0 Sack |
| 28. | 4.00 | Week 07, 2025 | Den | NYGNYG | 2 Tack, 2 Ass |
| 28. | 4.00 | Week 05, 2024 | Den | LV LV | 2 Tack, 2 Ass |
| 28. | 4.00 | Week 18, 2023 | Den | @LV@LV | 3 Tackles, 1 Assist |
| 28. | 4.00 | Week 10, 2023 | Den | @Buf@Buf | 2 Tackles, 2 Assists |
| 28. | 4.00 | Week 04, 2023 | Den | @Chi@Chi | 4 Tackles |
| 28. | 4.00 | Week 04, 2022 | Den | @LV@LV | 4 Tackles |
| 28. | 4.00 | Week 14, 2021 | SF | @CIN@CIN | 2 Tackles, 2 Assists |
| 28. | 4.00 | Week 02, 2021 | SF | @PHI@PHI | 4 Tackles |
| 28. | 4.00 | Week 17, 2020 | SF | SEASEA | 2 Tackles, 2 Assists |
| 28. | 4.00 | Week 02, 2020 | SF | @NYJ@NYJ | 3 Tackles, 1 Assist |
| 28. | 4.00 | Week 12, 2019 | SF | GBGB | 4 Tackles |
| 28. | 4.00 | Week 06, 2019 | SF | @LAR@LAR | 3 Tackles, 1 Assist |
| 28. | 4.00 | Week 14, 2018 | SF | DenDen | 2 Tackles, 2 Assists |
| 28. | 4.00 | Week 07, 2017 | SF | DalDal | 4 Tackles |
| 42. | 3.00 | Week 06, 2025 | Den | @NYJ@NYJ | 1 Tack, 2 Ass |
| 42. | 3.00 | Week 16, 2024 | Den | @LAC@LAC | 1 Tack, 1 Ass, 1 PD |
| 42. | 3.00 | Week 11, 2024 | Den | AtlAtl | 2 Tack, 1 Ass |
| 42. | 3.00 | Week 10, 2024 | Den | @KC @KC | 2 Tack, 1 Ass |
| 42. | 3.00 | Week 09, 2024 | Den | @Bal@Bal | 2 Tack, 1 Ass |
| 42. | 3.00 | Week 02, 2024 | Den | PitPit | 3 Tack |
| 42. | 3.00 | Week 01, 2024 | Den | @Sea@Sea | 2 Tack, 1 Ass |
| 42. | 3.00 | Week 07, 2023 | Den | GBGB | 2 Tackles, 1 Assist |
| 42. | 3.00 | Week 01, 2023 | Den | LVLV | 2 Tackles, 1 Assist |