*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 15.00 | Week 08, 2024 | SF | DalDal | 5 Tack, 1 Ass, 1 Int, 1 FF, 1 PD |
| 1. | 15.00 | Week 02, 2023 | SF | @LAR@LAR | 8 Tackles, 1 Assist, 1 Int, 1 PD |
| 3. | 14.00 | Week 07, 2024 | SF | KC KC | 6 Tack, 2 Ass, 1 Int, 1 PD |
| 4. | 12.00 | Week 04, 2022 | SF | LARLAR | 5 Tackles, 3 Assists, 1.0 Sack |
| 5. | 11.00 | Week 06, 2023 | SF | @Cle@Cle | 4 Tackles, 1 Assist, 1 Int, 1 PD |
| 6. | 10.00 | Week 17, 2023 | SF | @Was@Was | 2 Tackles, 1 Assist, 1 Int, 2 PD |
| 6. | 10.00 | Week 15, 2023 | SF | @Ari@Ari | 8 Tackles, 1 Assist, 1 PD |
| 6. | 10.00 | Week 01, 2023 | SF | @Pit@Pit | 8 Tackles, 2 Assists |
| 6. | 10.00 | Week 16, 2022 | SF | WasWas | 6 Tackles, 3 Assists, 1 PD |
| 6. | 10.00 | Week 15, 2022 | SF | @Sea@Sea | 9 Tackles, 1 Assist |
| 11. | 9.00 | Week 17, 2024 | SF | DetDet | 5 Tack, 4 Ass |
| 11. | 9.00 | Week 06, 2024 | SF | @Sea@Sea | 6 Tack, 2 Ass, 1 PD |
| 11. | 9.00 | Week 05, 2024 | SF | AriAri | 3 Tack, 5 Ass, 1 PD |
| 14. | 8.00 | Week 11, 2024 | SF | SeaSea | 8 Tack |
| 14. | 8.00 | Week 05, 2022 | SF | @Car@Car | 4 Tackles, 4 Assists |
| 14. | 8.00 | Week 02, 2021 | SF | @PHI@PHI | 4 Tackles, 1 Assist, 3 PD |
| 17. | 7.00 | Week 10, 2024 | SF | @TB @TB | 3 Tack, 4 Ass |
| 17. | 7.00 | Week 12, 2023 | SF | @Sea@Sea | 4 Tackles, 3 Assists |
| 17. | 7.00 | Week 10, 2023 | SF | @Jac@Jac | 4 Tackles, 3 Assists |
| 17. | 7.00 | Week 18, 2022 | SF | AriAri | 6 Tackles, 1 Assist |
| 17. | 7.00 | Week 17, 2022 | SF | @LV@LV | 4 Tackles, 3 Assists |
| 17. | 7.00 | Week 13, 2022 | SF | MiaMia | 1 Tackle, 1 Int, 1 PD |
| 23. | 6.00 | Week 15, 2024 | SF | LARLAR | 2 Tack, 2 Ass, 2 PD |
| 23. | 6.00 | Week 12, 2024 | SF | @GB @GB | 2 Tack, 4 Ass |
| 23. | 6.00 | Week 08, 2023 | SF | CinCin | 4 Tackles, 2 Assists |
| 23. | 6.00 | Week 14, 2022 | SF | TBTB | 3 Tackles, 2 Assists, 1 PD |
| 23. | 6.00 | Week 03, 2022 | SF | @Den@Den | 3 Tackles, 2 Assists, 1 PD |
| 28. | 5.00 | Week 16, 2024 | SF | @Mia@Mia | 2 Tack, 2 Ass, 1 PD |
| 28. | 5.00 | Week 02, 2024 | SF | @Min@Min | 2 Tack, 3 Ass |
| 28. | 5.00 | Week 01, 2024 | SF | NYJNYJ | 3 Tack, 1 Ass, 1 PD |
| 28. | 5.00 | Week 14, 2023 | SF | SeaSea | 2 Tackles, 1 Assist, 2 PD |
| 28. | 5.00 | Week 04, 2023 | SF | AriAri | 4 Tackles, 1 Assist |
| 28. | 5.00 | Week 03, 2023 | SF | NYGNYG | 4 Tackles, 1 Assist |
| 28. | 5.00 | Week 12, 2022 | SF | NONO | 5 Tackles |
| 35. | 4.00 | Week 04, 2024 | SF | NE NE | 2 Tack, 1 Ass, 1 PD |
| 35. | 4.00 | Week 03, 2024 | SF | @LAR@LAR | 3 Tack, 1 Ass |
| 35. | 4.00 | Week 16, 2023 | SF | BalBal | |
| 35. | 4.00 | Week 07, 2023 | SF | @Min@Min | 2 Tackles, 2 Assists |
| 35. | 4.00 | Week 05, 2023 | SF | DalDal | 1 Tackle, 2 Assists, 1 PD |
| 35. | 4.00 | Week 11, 2022 | SF | @Ari@Ari | 3 Tackles, 1 Assist |
| 35. | 4.00 | Week 07, 2022 | SF | KCKC | 2 Tackles, 2 Assists |
| 42. | 3.00 | Week 11, 2023 | SF | TBTB | 1 Tackle, 1 Assist, 1 PD |
| 42. | 3.00 | Week 13, 2021 | SF | @SEA@SEA | 3 Tackles |
| 42. | 3.00 | Week 01, 2021 | SF | @DET@DET | 2 Tackles, 1 Assist |
| 45. | 2.00 | Week 08, 2022 | SF | @LAR@LAR | 2 Tackles |
| 45. | 2.00 | Week 06, 2022 | SF | @Atl@Atl | 1 Tackle, 1 Assist |
| 45. | 2.00 | Week 15, 2021 | SF | ATLATL | 2 Assists |
| 45. | 2.00 | Week 14, 2021 | SF | @CIN@CIN | 2 Tackles |
| 45. | 2.00 | Week 12, 2021 | SF | MINMIN | 2 Tackles |
| 50. | 1.00 | Week 14, 2024 | SF | ChiChi | 1 Tack |