*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 17.00 | Week 01, 2022 | SF | @CHI@CHI | 9 Tackles, 2 Assists, 1 Int, 1 PD |
| 2. | 16.00 | Week 04, 2022 | SF | LARLAR | 3 Tackles, 1 Assist, 1 Int, 1 TD, 1 PD |
| 3. | 14.00 | Week 13, 2025 | Den | @Was@Was | 10 Tack, 3 Ass, 1 PD |
| 3. | 14.00 | Week 10, 2023 | SF | @Jac@Jac | 5 Tackles, 3 Assists, 1 Int, 1 PD |
| 5. | 13.00 | Week 10, 2025 | Den | LV LV | 5 Tack, 4 Ass, 1.00 Sack |
| 5. | 13.00 | Week 01, 2025 | Den | TenTen | 7 Tack, 3 Ass, 1 FF |
| 5. | 13.00 | Week 15, 2022 | SF | @Sea@Sea | 4 Tackles, 1 Assist, 1.0 Sack, 1 FF, 1 PD |
| 8. | 12.00 | Week 12, 2022 | SF | NONO | 6 Tackles, 3 Assists, 1 FF |
| 9. | 11.00 | Week 09, 2025 | Den | @Hou@Hou | 5 Tack, 4 Ass, 2 PD |
| 9. | 11.00 | Week 01, 2023 | SF | @Pit@Pit | 5 Tackles, 1 Int, 1 PD |
| 11. | 10.00 | Week 06, 2025 | Den | @NYJ@NYJ | 4 Tack, 1 Ass, 1.00 Sack, 1 PD |
| 11. | 10.00 | Week 02, 2025 | Den | @Ind@Ind | 5 Tack, 5 Ass |
| 11. | 10.00 | Week 08, 2023 | SF | CinCin | 8 Tackles, 2 Assists |
| 11. | 10.00 | Week 07, 2022 | SF | KCKC | 2 Tackles, 2 Assists, 1 Int, 1 PD |
| 11. | 10.00 | Week 05, 2022 | SF | @Car@Car | 2 Tackles, 3 Assists, 1.0 Sack, 1 PD |
| 16. | 9.00 | Week 07, 2023 | SF | @Min@Min | 7 Tackles, 2 Assists |
| 16. | 9.00 | Week 17, 2022 | SF | @LV@LV | 4 Tackles, 5 Assists |
| 16. | 9.00 | Week 16, 2022 | SF | WasWas | 4 Tackles, 4 Assists, 1 PD |
| 19. | 8.00 | Week 05, 2025 | Den | @Phi@Phi | 4 Tack, 3 Ass, 1 PD |
| 19. | 8.00 | Week 03, 2025 | Den | @LAC@LAC | 4 Tack, 2 Ass, 2 PD |
| 19. | 8.00 | Week 15, 2024 | SF | LARLAR | 2 Tack, 6 Ass |
| 19. | 8.00 | Week 10, 2022 | SF | LACLAC | 1 Tackle, 1 Assist, 1 Int, 1 PD |
| 19. | 8.00 | Week 08, 2022 | SF | @LAR@LAR | 6 Tackles, 2 Assists |
| 19. | 8.00 | Week 02, 2022 | SF | SeaSea | 5 Tackles, 1 Assist, 2 PD |
| 25. | 7.00 | Week 11, 2025 | Den | KC KC | 3 Tack, 3 Ass, 1 PD |
| 25. | 7.00 | Week 08, 2025 | Den | DalDal | 2 Tack, 5 Ass |
| 25. | 7.00 | Week 07, 2025 | Den | NYGNYG | 4 Tack, 1 Ass, 2 PD |
| 25. | 7.00 | Week 03, 2024 | SF | @LAR@LAR | 4 Tack, 3 Ass |
| 25. | 7.00 | Week 06, 2023 | SF | @Cle@Cle | 5 Tackles, 2 Assists |
| 25. | 7.00 | Week 03, 2023 | SF | NYGNYG | 1 Tackle, 1 Int, 1 PD |
| 31. | 6.00 | Week 17, 2024 | SF | DetDet | 5 Tack, 1 Ass |
| 31. | 6.00 | Week 16, 2024 | SF | @Mia@Mia | 2 Tack, 4 Ass |
| 31. | 6.00 | Week 11, 2022 | SF | @Ari@Ari | 5 Tackles, 1 Assist |
| 31. | 6.00 | Week 06, 2022 | SF | @Atl@Atl | 5 Tackles, 1 Assist |
| 35. | 5.00 | Week 14, 2025 | Den | @LV @LV | 4 Tack, 1 Ass |
| 35. | 5.00 | Week 18, 2024 | SF | @Ari@Ari | 4 Tack, 1 Ass |
| 35. | 5.00 | Week 14, 2024 | SF | ChiChi | 2 Tack, 3 Ass |
| 35. | 5.00 | Week 04, 2023 | SF | AriAri | 4 Tackles, 1 Assist |
| 35. | 5.00 | Week 02, 2023 | SF | @LAR@LAR | 2 Tackles, 3 Assists |
| 35. | 5.00 | Week 14, 2021 | SF | @CIN@CIN | 4 Tackles, 1 Assist |
| 35. | 5.00 | Week 08, 2021 | SF | @CHI@CHI | 4 Tackles, 1 Assist |
| 42. | 4.00 | Week 18, 2022 | SF | AriAri | 3 Tackles, 1 Assist |
| 42. | 4.00 | Week 14, 2022 | SF | TBTB | 3 Tackles, 1 Assist |
| 42. | 4.00 | Week 03, 2022 | SF | @Den@Den | 3 Tackles, 1 Assist |
| 42. | 4.00 | Week 13, 2021 | SF | @SEA@SEA | 3 Tackles, 1 Assist |
| 42. | 4.00 | Week 10, 2021 | SF | LARLAR | 3 Tackles, 1 PD |
| 47. | 3.00 | Week 12, 2021 | SF | MINMIN | 2 Tackles, 1 PD |
| 47. | 3.00 | Week 11, 2021 | SF | @Jac@Jac | 2 Tackles, 1 Assist |
| 47. | 3.00 | Week 09, 2021 | SF | ARIARI | 2 Tackles, 1 Assist |
| 50. | 2.00 | Week 07, 2021 | SF | INDIND | 2 Assists |