| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Miguel Amaya | C | ChN | 26 | |
| Ryan Jeffers | C | Min | 27 | |
| Joshua Bell | 1B | Was | 32 | |
| Kyle Manzardo | 1B | Cle | 24 | |
| Josh Naylor | 1B | Ari | 27 | |
| Andrés Gimenez | 2B | Tor | 26 | |
| Romy Gonzalez | 2B (1B) | Bos | 28 | |
| Matt McLain | 2B | Cin | 25 | |
| Bo Bichette | SS | Tor | 27 | |
| Carlos Correa | SS | Min | 30 | |
| Trevor Story | SS | Bos | 32 | |
| Nolan Arenado | 3B | StL | 34 | |
| Eugenio Suarez | 3B | Ari | 33 | |
| Miguel Vargas | 3B | ChA | 25 | |
| Matt Vierling | 3B | Det | 28 | March 27, 2025:10 Day IL |
| Harrison Bader | OF | Min | 30 | |
| Evan Carter | OF | Tex | 22 | |
| Kike Hernandez | OF (1B,2B) | LAD | 33 | |
| Brandon Marsh | OF | Phi | 27 | April 20, 2025:10 Day IL |
| Lars Nootbaar | OF | StL | 27 | |
| Anthony Santander | OF | Tor | 30 | |
| Seiya Suzuki | OF | ChN | 30 | |
| Tyler Anderson | SP | LAA | 35 | |
| Garrett Crochet | SP | Bos | 25 | |
| Shota Imanaga | SP | ChN | 31 | |
| Zack Littell | SP | TB | 29 | |
| Tyler Mahle | SP | Tex | 30 | |
| Roki Sasaki | SP | LAD | 23 | |
| Brady Singer | SP | Cin | 28 | |
| Justin Verlander | SP | SF | 42 | |
| Logan Webb | SP | SF | 28 | |
| Bryan Woo | SP | Sea | 25 | |
| Tanner Scott | RP | LAD | 30 |